Protective Effect of Plant Sterols against Chemically Induced Colon Tumors in Rat&
نویسندگان
چکیده
Diets rich in vegetables are associated with a low incidence of colon cancer. Since plant sterols are plentiful in vegetarian diets, we studied the effect of fl-sitosterol on colon tumor formation in rats treated with the carcinogen N-methyl-N-nitro sourea. We demonstrated that $-sitosterol nullified in part the effect of this direct-acting carcinogen on the colon. We suggest that plant sterols may have a protective dietary action to retard colon tumor formation. The beneficial effects of vegetarian diets may be enhanced because of the presence of these compounds.
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